You are quite correct and I apologize for the tone of my posts, and I should have gone the way you suggested (as in Star Trek embracing transhumanism). I suppose I have been stewing about this subject for many years and basically exploded. Again I am sorry for that. I did allude to it the way I wanted to go with mentioning Khan Ascendant, just wish I had the foresight to have gone that way.You're just complaining, in effect, that a banana should taste more citrusy. Now, if you wanted to discuss what Star Trek might look like if it had embraced Transhumanism, that might be an interesting discussion.
I also don't want to imply I dislike Star Trek, to be brutally honest I love almost all aspects of it and it is for me, my favorite sci-fi series. I think my ShadowRun (RPG) bias was showing thru (love of cyberware...LoL) I have seen every episode (I either own the DVD's or have downloaded them) of all the different series(original series, next gen, DS9, Voyager, Enterprise, all the movies, and including most of the fan based stuff that recently has been done (Prelude to Axanar for example)and consider myself a Trekkie at heart.
As far as the inevitability of human genetic manipulation, cloning, integration of humans and machine, biosyntectic replacements of all major organs for all those that need them....etc IMHO yes I truly believe it is inevitable. We can already see these technology's emerging and there are already precedence's of them starting to be integrated into our lives. I also believe andriods/robotics will also be a massive part of human culture(again already started).
here's a view of homo-novus that I could see becoming a reality in the near future (nootropic drugs [brain enhancing drugs, the first step in creating the next stage in our evolution] are a reality, just not refined to this degree)
http://future.wikia.com/wiki/Homo_Novus_%28species%29